CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8123
Family Name Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta inhibitor SureCN14427362 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00385719 Functional Category Bioactive
Superfamily Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta Binder Superfamily 2
Class Class 712

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Aurora kinase B and Tyrosine-protein kinase Lck Inhibitor CGP-... 2 29
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BIUF2 family 25 11
Aurora kinase A and Aurora kinase B inhibitor 3uol family 6 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 7
5-hydroxytryptamine receptor 6 ligand 3-(benzenesulfonyl)-N,5-... 4 1
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 2 3
Aurora kinase A and Cyclin-dependent kinase 1 inhibitor N-[4-[... 12 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
D(4) dopamine receptor and Alpha-1D adrenergic receptor ligand... 3 3
Cyclin-dependent kinase 2 and MAP kinase-activated protein kin... 3 0
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
Casein kinase II subunit alpha inhibitor N-[2-chloro-5-[[3-cya... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Activated CDC42 kinase 1 inhibitor AGN-PC-078WDN family 7 2
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C9 l... 2 5
Glucocorticoid receptor ligand N-ethyl-4-fluoro-N-[3,3,3-trifl... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385719 CHEMBL178785 Bioactive SureCN14427362
CFAMM00385718 CHEMBL178769 Bioactive SureCN14427538
CFAMM00385717 CHEMBL367150 Bioactive AGN-PC-046PXZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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