CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8124
Family Name NS5B protein inhibitor AGN-PC-00A17Z family
No. of Seeds 1 No. of Other Members 23
Family Centroid CFAMM00385727 Functional Category Bioactive with Natural Product
Superfamily Wee1-like protein kinase and Serine/threonine-protein kinase Chk1 Binder Superfamily
Class Class 2321

Cousin Family NamesSeedsMembers
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 4
NS5B protein inhibitor AC1NQMYG family 6 12
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
NS5B protein inhibitor AC1O5AET family 3 1
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Plasma kallikrein and Coagulation factor VII inhibitor 2-[(3E)... 15 49
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Beta-2 adrenergic receptor ligand SureCN4598646 family 7 7
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Coagulation factor X and Urokinase-type plasminogen activator ... 8 10
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Coagulation factor VII and Tissue factor inhibitor 2-[3-(5-car... 3 2
Coagulation factor X and Prothrombin inhibitor SureCN6292901 f... 2 0
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Microtubule-associated protein tau and Glycogen synthase kinas... 9 15
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-071TED family 9 12
Thrombopoietin receptor ligand AGN-PC-077M9L family 2 4


External ID

Functional Category

Molecule Name

CFAMM00385727 CHEMBL178784 Bioactive AGN-PC-00A17Z

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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