CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8126
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-PC-075BJB family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00215521 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-specific 3',5'-cyclic phosphodiesterase 4D Binder Superfamily 2
Class Class 2504

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Heat shock protein HSP 90-alpha Inhibitor 8-benzo[1,3]dioxol-,... 5 83
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
TGF-beta receptor type-1 Ligand SB-431542 Family 2 42
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 9
Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) ... 24 9
Lysine--tRNA ligase and Dual specificity protein kinase CLK4 i... 4 27
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 6
Smoothened homolog inhibitor N-[3-(1H-benzimidazol-2-yl)phenyl... 2 1
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 6 17
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 11 4
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Coagulation factor X and Cationic trypsin inhibitor SureCN6944... 2 5
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385755 CHEMBL362175 Bioactive AGN-PC-075BJ8

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

39301 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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