CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 inhibitor AGN-PC-07ZYDO family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00316146 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Binder Superfamily
Class Class 1666

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
D(4) dopamine receptor Ligand Fauc 113 Family 14 96
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
TGF-beta receptor type-1 Ligand 4-(3-pyridin-2-yl-1h-pyrazol-4... 3 63
TGF-beta receptor type-1 Ligand Naphthyridine Inhibitor Family 3 6
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 5 10
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Metabotropic glutamate receptor 5 Ligand 5-(2-methylquinolin-7... 4 3
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 2 4
Acetylcholinesterase and Cholinesterase inhibitor 3,8-DIAMINO-... 2 3
Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... 4 12
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00AP1L ... 14 7
Metabotropic glutamate receptor 5 ligand AGN-PC-075GBZ family 2 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 4
Microtubule-associated protein tau inhibitor 4-[4-[(E)-2-[5-[(... 1 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 6
Casein kinase I isoform delta and Casein kinase I isoform epsi... 1 0
Serine/threonine-protein kinase Chk1 inhibitor 5-[7-(2-morphol... 2 2
CGMP-dependent protein kinase inhibitor methyl 2-[[4-[5-(4-flu... 6 1
CGMP-dependent protein kinase inhibitor AGN-PC-078XQ0 family 1 1
Transient receptor potential cation channel subfamily V member... 1 0
TGF-beta receptor type-1 ligand N-(3-cyanophenyl)-2-[3-(6-meth... 4 5


External ID

Functional Category

Molecule Name

CFAMM00316146 CHEMBL1089773 Bioactive AGN-PC-07ZYDO
CFAMM00316145 CHEMBL1092926 Bioactive AGN-PC-07T7SK

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



26841 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543