CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8154
Family Name Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydroxy-3-(6-methoxypyridin-3-yl)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)nonanoic acid family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00385941 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-V Binder Superfamily 4
Class Class 851

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand Piogli... 2 29
Histamine H1 receptor Ligand Mepyramine Family 5 65
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-... 13 1
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2924568 f... 1 0
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2489170 f... 8 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 8 3
Integrin beta-3 and Integrin alpha-V inhibitor SureCN8335217 f... 2 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6223678 f... 14 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6220269 f... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-074ASZ f... 5 0
Peroxisome proliferator-activated receptor gamma and Cytochrom... 1 1
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Integrin beta-3 and Integrin alpha-V inhibitor SureCN244675 fa... 1 0
Farnesyl pyrophosphate synthase inhibitor [phosphono-[[4-(4-pr... 6 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 1
4-[(4-pyridin-1-ium-2-ylpiperazin-1-yl)methyl]chromen-2-one NP... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00385943 CHEMBL186206 Bioactive SureCN4251938
CFAMM00385942 CHEMBL180489 Bioactive SureCN6358670
CFAMM00385941 CHEMBL179069 Bioactive (3S,7S)-7-hydroxy-3-(6-methoxypyridin-3-yl)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)nonanoic acid
CFAMM00385945 CHEMBL369530 Bioactive (3S,7R)-7-hydroxy-3-(6-methoxypyridin-3-yl)-9-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)nonanoic acid
CFAMM00385944 CHEMBL181366 Bioactive SureCN8079608

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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