CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8160
Family Name Pol polyprotein inhibitor AC1LAMTL family
No. of Seeds 11 No. of Other Members 15
Family Centroid CFAMM00385956 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 14
Class Class 3367

Cousin Family NamesSeedsMembers
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
Pol polyprotein inhibitor Dmp 323 family 11 44
Pol polyprotein inhibitor 3-[[(4R,5R,6R)-6-[2-(4-fluorophenyl)... 7 6
Pol polyprotein inhibitor (4R,5R,6S,7R)-1,3,4,7-tetrabenzyl-5,... 12 29
Pol polyprotein inhibitor 183860-48-2 family 5 1
Pol polyprotein inhibitor 3-[(4R,5R,6R)-3-[3-[(E)-1-amino-2-hy... 2 4
Pol polyprotein inhibitor 3-[(4R,5R,6R)-4-benzyl-3-(3-carbamoy... 3 1
Pol polyprotein inhibitor (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bi... 3 2
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 11 9
C-C chemokine receptor type 3 ligand 1-(3-acetylphenyl)-3-[3-[... 9 1
Pol polyprotein inhibitor DMP-450 family 9 4
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 1 5
Beta-secretase 1 and Cathepsin D inhibitor (4S)-N-[(2S,3R)-4-[... 3 0
Pol polyprotein inhibitor Cyclic Urea 64 family 12 1
Pol polyprotein inhibitor AC1LAMTC family 6 0
Pol polyprotein inhibitor AC1LAMVF family 2 0
Neuropeptide Y receptor type 5 ligand 3-(4-benzylphenyl)-1-[(1... 2 4
Pol polyprotein inhibitor AC1LABTT family 2 0
Pol polyprotein inhibitor 4-benzyl-N-[(2S)-1-[[(2S,3R,4S,5S)-5... 3 0
Pol polyprotein inhibitor AC1LADP4 family 2 0
Pol polyprotein inhibitor AC1LAH82 family 2 1
Pol polyprotein inhibitor Cyclic Urea deriv. 9l family 1 0
Pol polyprotein inhibitor (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihyd... 2 0
Sodium-dependent noradrenaline transporter inhibitor SureCN408... 5 12
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
C-C chemokine receptor type 3 ligand 1-(3-cyanophenyl)-3-[2-[2... 2 1
Cathepsin D and Beta-secretase 1 inhibitor N-[(2S,3R)-4-[[1-[3... 1 0


External ID

Functional Category

Molecule Name

CFAMM00385976 CHEMBL285282 Bioactive AC1LAMTU
CFAMM00385956 CHEMBL36862 Bioactive AC1LAMTL
CFAMM00385969 CHEMBL39592 Bioactive AC1LAMTR
CFAMM00385962 CHEMBL420503 Bioactive (4R,5R,6R)-4-benzyl-1,3-bis[[4-fluoro-3-(methylamino)phenyl]methyl]-5-hydroxy-6-(2-phenylethyl)-1,3-diazinan-2-one
CFAMM00385975 CHEMBL181166 Bioactive (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[3-(methylamino)phenyl]-6-(2-phenylethyl)-1,3-diazinan-2-one
CFAMM00385955 CHEMBL179250 Bioactive (4R,5R,6R)-1,3-bis(3-aminophenyl)-4-benzyl-5-hydroxy-6-(2-phenylethyl)-1,3-diazinan-2-one
CFAMM00385960 CHEMBL286390 Bioactive AC1LAMTO
CFAMM00385972 CHEMBL286794 Bioactive AC1LAMNF
CFAMM00385964 CHEMBL179103 Bioactive (4R,5R,6R)-1,3-bis(3-amino-4-fluorophenyl)-4-benzyl-5-hydroxy-6-(2-phenylethyl)-1,3-diazinan-2-one
CFAMM00385957 CHEMBL289393 Bioactive AC1LAMOL
CFAMM00385970 CHEMBL181514 Bioactive (4R,5R,6R)-1,3-bis(4-amino-3-fluorophenyl)-4-benzyl-5-hydroxy-6-(2-phenylethyl)-1,3-diazinan-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



80821 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543