CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8170
Family Name NS5B protein inhibitor (2E)-1-cyclohexyl-2-(2-fluoro-4-oxocyclohexa-2,5-dien-1-ylidene)-3H-benzimidazole-5-carboxylic acid family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00386032 Functional Category Bioactive
Superfamily NS5B protein and Bile acid receptor Binder Superfamily
Class Class 1253

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Thromboxane A2 receptor ligand AC1NSKJR family 13 42
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Thyroid hormone receptor beta ligand CHEMBL1325165 family 1 6
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Serine/threonine-protein kinase Chk2 inhibitor SureCN3919556 f... 4 8
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Smoothened homolog inhibitor N-[3-(1H-benzimidazol-2-yl)phenyl... 2 1
Vascular endothelial growth factor receptor 2 and Fibroblast g... 1 6
Coagulation factor X inhibitor AGN-PC-07C10A family 3 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN2... 1 2
NS5B protein and Genome polyprotein inhibitor AC1LAG00 family 1 19
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
Gastrin/cholecystokinin type B receptor ligand AGN-PC-077L8M f... 24 10
Type-1A angiotensin II receptor ligand 2-[4-[[2-butyl-5-(tert-... 1 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
NS5B protein inhibitor AGN-PC-00HCFC family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386031 CHEMBL179257 Bioactive AGN-PC-0055KQ
CFAMM00386032 CHEMBL179256 Bioactive (2E)-1-cyclohexyl-2-(2-fluoro-4-oxocyclohexa-2,5-dien-1-ylidene)-3H-benzimidazole-5-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46272 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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