CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibitor 2-tert-butyl-1'-(2,7-dimethyl-3H-benzimidazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00316178 Functional Category Bioactive
Superfamily Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 Binder Superfamily
Class Class 3226

Cousin Family NamesSeedsMembers
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 3 4
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9RSG ... 6 5
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 2
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 1


External ID

Functional Category

Molecule Name

CFAMM00316181 CHEMBL1958373 Bioactive 2-tert-butyl-1'-(7-methyl-3H-benzimidazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
CFAMM00316178 CHEMBL1958374 Bioactive 2-tert-butyl-1'-(2,7-dimethyl-3H-benzimidazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
CFAMM00316177 CHEMBL1089882 Bioactive 6-(1-methylpyrazol-4-yl)-1'-[(2E)-2-(2-methyl-1H-pyrazol-5-ylidene)benzimidazole-5-carbonyl]spiro[3H-pyrano[2,3-c]pyridine-2,4'-piperidine]-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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