CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8184
Family Name Serine/threonine-protein kinase PLK1 and Serine/threonine-protein kinase PLK3 inhibitor 5-[5,6-Bis(Methyloxy)-1h-Benzimidazol-1-Yl]-3-{[1-(2-Chlorophenyl)ethyl]oxy}-2-Thiophenecarboxamide family
No. of Seeds 14 No. of Other Members 1
Family Centroid CFAMM00386118 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase PLK1 and Cytochrome P450 2D6 Binder Superfamily
Class Class 2800

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor GSK461364 Family 40 84
Serine/threonine-protein kinase PLK1 and Cytochrome P450 2C9 i... 7 0
Serine/threonine-protein kinase PLK1 and Death-associated prot... 2 1
Serine/threonine-protein kinase PLK1 inhibitor SureCN2523858 f... 4 2


External ID

Functional Category

Molecule Name

CFAMM00386116 CHEMBL480545 Bioactive AGN-PC-050ULW
CFAMM00386115 CHEMBL514162 Bioactive GW852849X
CFAMM00386114 CHEMBL474029 Bioactive AGN-PC-050ULK
CFAMM00386113 CHEMBL474028 Bioactive SureCN5062225
CFAMM00386112 CHEMBL474054 Bioactive AGN-PC-050ULM
CFAMM00386118 CHEMBL222419 Bioactive 5-[5,6-Bis(Methyloxy)-1h-Benzimidazol-1-Yl]-3-{[1-(2-Chlorophenyl)ethyl]oxy}-2-Thiophenecarboxamide
CFAMM00386111 CHEMBL474053 Bioactive SureCN5065836
CFAMM00386110 CHEMBL1794069 Bioactive GSK571989A

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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