CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8191
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[carboxymethyl-[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]amino]ethyl-[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]amino]acetic acid;zinc family
No. of Seeds 10 No. of Other Members 5
Family Centroid CFAMM00348542 Functional Category Bioactive
Superfamily Stromelysin-1 and Carbonic anhydrase 2 Binder Superfamily
Class Class 3217

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand T... 3 35
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 8 4
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor AGN-P... 5 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
B1 bradykinin receptor ligand N-[(4S)-1-ethyl-3,3-dimethylpipe... 10 4
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-5-oxo-5-... 2 15
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (3R)-3-... 3 2
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 6 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[car... 1 0
NS3 inhibitor 6-[[(2S)-1-[[(2S)-1-[(2S)-2-[[1-(cyclopropylamin... 2 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor AGN-PC... 2 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386154 CHEMBL36194 Bioactive 2-[2-[2-[2-[carboxymethyl-[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]amino]ethoxy]ethoxy]ethyl-[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]amino]acetic acid
CFAMM00386160 CHEMBL1795051 Bioactive 2-[2-[2-[2-[carboxymethyl-[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]amino]ethoxy]ethoxy]ethyl-[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]amino]acetic acid;zinc
CFAMM00386159 CHEMBL1795052 Bioactive 2-[2-[2-[2-[carboxymethyl-[2-oxo-2-[(4-sulfamoylphenyl)methylamino]ethyl]amino]ethoxy]ethoxy]ethyl-[2-oxo-2-[(4-sulfamoylphenyl)methylamino]ethyl]amino]acetic acid;zinc
CFAMM00386152 CHEMBL286449 Bioactive ST51005521
CFAMM00386158 CHEMBL285436 Bioactive 2-[2-[carboxymethyl-[2-oxo-2-[(4-sulfamoylphenyl)methylamino]ethyl]amino]ethyl-[2-oxo-2-[(4-sulfamoylphenyl)methylamino]ethyl]amino]acetic acid
CFAMM00386157 CHEMBL1795055 Bioactive 2-[2-[carboxymethyl-[2-oxo-2-[(4-sulfamoylphenyl)methylamino]ethyl]amino]ethyl-[2-oxo-2-[(4-sulfamoylphenyl)methylamino]ethyl]amino]acetic acid;zinc

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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