CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8197
Family Name Peroxisome proliferator-activated receptor gamma ligand AGN-PC-075BWL family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00386181 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Binder Superfamily
Class Class 2976

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
NS5B protein inhibitor AC1O5AET family 3 1
Glucagon receptor ligand 3-[[4-[(2S)-2-[5-(trifluoromethoxy)-1... 1 2
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Proteinase-activated receptor 1 ligand (3R,3aR,4S,5R,6S,7aS)-5... 2 3
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 1 2
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 7 1
Proteinase-activated receptor 1 ligand (3R,3aS,4S,4aR,8aS,9aR)... 1 11
Peroxisome proliferator-activated receptor gamma and Peroxisom... 9 0
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Peroxisome proliferator-activated receptor gamma ligand SureCN... 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-071TED family 9 12
Peroxisome proliferator-activated receptor delta ligand 2-[4-[... 4 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386181 CHEMBL179542 Bioactive AGN-PC-075BWL
CFAMM00386187 CHEMBL181628 Bioactive SureCN5174266
CFAMM00386193 CHEMBL361395 Bioactive SureCN5173307
CFAMM00386192 CHEMBL192691 Bioactive (2S)-2-[3-[[1-(4-methoxyphenyl)-2-methyl-5-(trifluoromethoxy)indol-3-yl]methyl]phenoxy]propanoic acid
CFAMM00386182 CHEMBL181937 Bioactive SureCN5172443

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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