CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8201
Family Name Mitogen-activated protein kinase 14 inhibitor N-[(2R)-1-amino-1-oxopropan-2-yl]-3-[5-chloro-4-[(2,4-difluorophenyl)methoxy]-6-oxopyrimidin-1-yl]-4-methylbenzamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00386262 Functional Category Bioactive
Superfamily PH-797804 Superfamily
Class Class 1294

Cousin Family NamesSeedsMembers
PH-797804 family 6 28
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
5-hydroxytryptamine receptor 7 ligand 4-[4-(2-ethoxyphenyl)pip... 2 5


External ID

Functional Category

Molecule Name

CFAMM00386262 CHEMBL1795684 Bioactive N-[(2R)-1-amino-1-oxopropan-2-yl]-3-[5-chloro-4-[(2,4-difluorophenyl)methoxy]-6-oxopyrimidin-1-yl]-4-methylbenzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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