CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8205
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor 203640-27-1 family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00386279 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 6
Class Class 2185

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Growth hormone receptor Ligand EP-51216 Family 34 390
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Histone deacetylase Inhibitor ST-5732 Family 8 6
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 4 19
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 2 14
Cathepsin L1 inhibitor Bio2_000267 family 9 1
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 1 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
Matrix metalloproteinase-14 and A disintegrin and metalloprote... 3 0
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2
Neprilysin and Endothelin-converting enzyme 1 inhibitor (2S)-2... 5 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor [2-(me... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL3... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386277 CHEMBL47971 Bioactive (2R)-2-[[5-[2-(4-ethylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]-3-(1H-indol-3-yl)propanoic acid
CFAMM00386280 CHEMBL50437 Bioactive (2R)-2-[[5-[2-(4-butylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]-3-(1H-indol-3-yl)propanoic acid
CFAMM00386279 CHEMBL297792 Bioactive 203640-27-1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26824 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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