CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8220
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform inhibitor 2-N-(2-chlorophenyl)-2-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2,9-dicarboxamide family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00386365 Functional Category Bioactive
Superfamily Beta-lactamase and Cellular tumor antigen p53 Binder Superfamily 12
Class Class 3906

Cousin Family NamesSeedsMembers
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 8
Estradiol 17-beta-dehydrogenase 2 inhibitor 5-(2-fluoro-3-meth... 1 3


External ID

Functional Category

Molecule Name

CFAMM00386367 CHEMBL1950036 Bioactive N-(2-chlorophenyl)-9-cyano-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2-carboxamide
CFAMM00386373 CHEMBL1796273 Bioactive 8-acetamido-N-(2-chlorophenyl)-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2-carboxamide
CFAMM00386366 CHEMBL1950035 Bioactive 2-N-(2-chlorophenyl)-9-N-ethyl-2-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2,9-dicarboxamide
CFAMM00386372 CHEMBL1796274 Bioactive methyl N-[2-[(2-chlorophenyl)-methylcarbamoyl]-4,5-dihydrothieno[3,2-d][1]benzoxepin-8-yl]carbamate
CFAMM00386365 CHEMBL1950034 Bioactive 2-N-(2-chlorophenyl)-2-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2,9-dicarboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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