CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8226
Family Name Mitogen-activated protein kinase 14 inhibitor 3-bromo-1-(2,6-difluorophenyl)-4-[(2,4-difluorophenyl)methoxy]-6-[(dimethylamino)methyl]pyridin-2-one family
No. of Seeds 5 No. of Other Members 11
Family Centroid CFAMM00386402 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 Binder Superfamily 3
Class Class 4624

Cousin Family NamesSeedsMembers
PH-797804 family 6 28
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Melanin-concentrating hormone receptor 1 ligand 1-[1-(1-methyl... 5 10
Mitogen-activated protein kinase 14 inhibitor 3-chloro-1-(2,6-... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-bromo-1-(2,6-d... 2 3
Mitogen-activated protein kinase 14 inhibitor 3-bromo-1-[2,6-d... 2 0
Mitogen-activated protein kinase 14 inhibitor 3-bromo-1-(2,6-d... 2 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-07CR9C ... 10 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03JNM7 fa... 1 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZB3M fa... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386410 CHEMBL1797203 Bioactive 3-bromo-4-[(2,4-difluorophenyl)methoxy]-1-(2,6-dimethylphenyl)-6-methylpyridin-2-one
CFAMM00386403 CHEMBL1797214 Bioactive 3-bromo-1-(2,6-difluorophenyl)-4-[(2,4-difluorophenyl)methoxy]-6-(morpholin-4-ylmethyl)pyridin-2-one
CFAMM00386402 CHEMBL1797212 Bioactive 3-bromo-1-(2,6-difluorophenyl)-4-[(2,4-difluorophenyl)methoxy]-6-[(dimethylamino)methyl]pyridin-2-one
CFAMM00386401 CHEMBL1797206 Bioactive 3-bromo-4-[(2,4-difluorophenyl)methoxy]-1-[4-(dimethylamino)-2,6-difluorophenyl]-6-methylpyridin-2-one
CFAMM00386407 CHEMBL1797123 Bioactive 3-bromo-1-(2,6-difluorophenyl)-4-[(2,4-difluorophenyl)methoxy]-6-methylpyridin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26815 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543