CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM823
Family Name Histamine H1 receptor and Potassium voltage-gated channel subfamily H member 2 ligand 2-[6-methoxy-3-[(1R)-1-pyrazin-2-ylethyl]-1H-inden-2-yl]-N,N-dimethylethanamine family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00316238 Functional Category Bioactive
Superfamily Histamine H1 receptor and Muscarinic acetylcholine receptor M1 Binder Superfamily 2
Class Class 3222

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 2
Glucocorticoid receptor ligand SureCN3894124 family 3 0
Lanosterol synthase inhibitor AGN-PC-07BZTX family 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00316237 CHEMBL1092258 Bioactive AGN-PC-07ZCLG
CFAMM00316236 CHEMBL1090186 Bioactive 2-[6-methoxy-3-[(1R)-1-(3-methoxypyrazin-2-yl)ethyl]-1H-inden-2-yl]-N,N-dimethylethanamine
CFAMM00316238 CHEMBL1090175 Bioactive 2-[6-methoxy-3-[(1R)-1-pyrazin-2-ylethyl]-1H-inden-2-yl]-N,N-dimethylethanamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27433 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543