CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8235
Family Name Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate receptor 3 ligand 1-[[6-[3-(4-fluorophenyl)propoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride family
No. of Seeds 12 No. of Other Members 0
Family Centroid CFAMM00386448 Functional Category Bioactive
Superfamily Sodium- and chloride-dependent glycine transporter 1 Inhibitor ALX-5407 Superfamily
Class Class 51

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Leukotriene A-4 hydrolase inhibitor 3-[3-(4-benzylphenoxy)prop... 2 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
Sigma non-opioid intracellular receptor 1 ligand tert-butyl 2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386447 CHEMBL1935575 Bioactive 1-[[1-methyl-6-(3-phenylpropoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386456 CHEMBL1935584 Bioactive 1-[[6-[(2S)-3-(4-fluorophenyl)-2-methylpropoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386446 CHEMBL1935577 Bioactive 1-[[6-[3-(3-fluorophenyl)propoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386455 CHEMBL1935585 Bioactive 1-[[6-[(2S)-2-[(4-fluorophenyl)methyl]butoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386451 CHEMBL1797509 Bioactive 1-[[1-methyl-6-(4-phenylbutoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
CFAMM00386460 CHEMBL1935583 Bioactive 1-[[6-[(2R)-3-(4-fluorophenyl)-2-methylpropoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386450 CHEMBL1935579 Bioactive 1-[[1-methyl-6-(3-phenylbutoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386459 CHEMBL1935580 Bioactive 1-[[1-methyl-6-(2-methyl-3-phenylpropoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386449 CHEMBL1935578 Bioactive 1-[[6-[3-(2-fluorophenyl)propoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386458 CHEMBL1935586 Bioactive 1-[[6-[(2R)-2-[(4-fluorophenyl)methyl]-3-methylbutoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386448 CHEMBL1935576 Bioactive 1-[[6-[3-(4-fluorophenyl)propoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride
CFAMM00386457 CHEMBL1935587 Bioactive 1-[[6-[(2S)-3-(4-chlorophenyl)-2-methylpropoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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