CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8237
Family Name Pol polyprotein inhibitor 3-[(4R,5R,6R)-4-benzyl-3-(3-carbamoylphenyl)-5-hydroxy-2-oxo-6-(2-phenylethyl)-1,3-diazinan-1-yl]benzamide family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00386470 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 21
Class Class 3367

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Beta-secretase 1 Inhibitor GSK-188909 Family 16 11
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Beta-secretase 1 and Cathepsin D inhibitor 3ixk family 2 9
Beta-secretase 1 and Cathepsin D inhibitor (1R,3S)-N-[(2S,3S)-... 2 25
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZFJZ family 1 3
Beta-secretase 1 and Cathepsin D inhibitor 3-(4-chloro-N-methy... 1 0
Pol polyprotein inhibitor 152928-55-7 family 23 2
Pol polyprotein inhibitor 183860-48-2 family 5 1
Pol polyprotein inhibitor 3-[(4R,5R,6R)-3-[3-[(E)-1-amino-2-hy... 2 4
Pol polyprotein inhibitor AC1LAMTL family 11 15
Pol polyprotein inhibitor (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bi... 3 2
Beta-secretase 1 inhibitor (2S)-2-[(3R)-3-acetamido-3-(2-methy... 3 0
C-C chemokine receptor type 3 and Sodium-dependent serotonin t... 12 2
Delta-type opioid receptor and Potassium voltage-gated channel... 3 2
C-C chemokine receptor type 2 ligand N-[2-[[(2S,3S)-1-[(2,4-di... 13 8
Cathepsin D and Cathepsin E inhibitor methyl (2S)-1-[(2R)-2-[[... 1 0
C-C chemokine receptor type 3 ligand 1-(3-acetylphenyl)-3-[3-[... 9 1
Pol polyprotein inhibitor DMP-450 family 9 4
Beta-secretase 1 inhibitor 1-N-[(1R,2S)-1-[(2R,4S)-4-butoxypip... 5 1
Pol polyprotein inhibitor 2,5-bis[(2-{[(benzyloxy)carbonyl]ami... 2 3
Pol polyprotein inhibitor AC1LAMTC family 6 0
Pol polyprotein inhibitor Enantiomer of AG1284 family 7 1
Pol polyprotein inhibitor AC1LAH82 family 2 1
Pol polyprotein inhibitor 3-amino-N-[(2S,3S,4R,5S)-5-[(3-amino... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386470 CHEMBL179761 Bioactive 3-[(4R,5R,6R)-4-benzyl-3-(3-carbamoylphenyl)-5-hydroxy-2-oxo-6-(2-phenylethyl)-1,3-diazinan-1-yl]benzamide
CFAMM00386469 CHEMBL290331 Bioactive AC1LAMOR
CFAMM00386467 CHEMBL366431 Bioactive 5-[(4R,5R,6R)-4-benzyl-3-(3-carbamoyl-4-fluorophenyl)-5-hydroxy-2-oxo-6-(2-phenylethyl)-1,3-diazinan-1-yl]-2-fluorobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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