CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8252
Family Name 72 kDa type IV collagenase and Collagenase 3 inhibitor 1-ethyl-N-hydroxy-4-[4-[4-(trifluoromethyl)phenoxy]phenyl]sulfonylpiperidine-4-carboxamide family
No. of Seeds 11 No. of Other Members 5
Family Centroid CFAMM00234860 Functional Category Bioactive
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 and 72 kDa type IV collagenase Binder Superfamily
Class Class 2056

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 15 129
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
D(3) dopamine receptor Ligand GR-218231 Family 4 17
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 3 28
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Collagenase 3 inhibitor N-hydro... 3 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Muscarinic acetylcholine receptor M2 ligand (2R)-4-cyclohexyl-... 12 0
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 15
Disintegrin and metalloproteinase domain-containing protein 17... 5 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Collagenase 3 and Interstitial collagenase inhibitor (3S,4R)-N... 9 8
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Interstitial collagenase inhibitor AGN-PC-075XO4 family 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 6 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 16
Disintegrin and metalloproteinase domain-containing protein 17... 12 1
Disintegrin and metalloproteinase domain-containing protein 17... 9 3
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-[(4-b... 3 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 4 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor N-hydro... 3 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-[4-[(... 5 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor 3-cyclo... 5 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 4
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
Interstitial collagenase and Matrix metalloproteinase-9 inhibi... 1 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 0
Collagenase 3 and Interstitial collagenase inhibitor 2-(4-brom... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386596 CHEMBL1801414 Bioactive N-hydroxy-1-(2-methoxyethyl)-4-[4-(4-propan-2-ylphenoxy)phenyl]sulfonylpiperidine-4-carboxamide
CFAMM00386600 CHEMBL1800089 Bioactive N-hydroxy-1-(2-morpholin-4-ylethyl)-4-[4-[4-(trifluoromethyl)phenoxy]phenyl]sulfonylpiperidine-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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