CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8274
Family Name Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-2-yl)-1,4-diazepan-1-yl]-morpholin-4-ylmethanone family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00386817 Functional Category Bioactive
Superfamily Orexin receptor type 1 and Orexin receptor type 2 Ligand MK-4305 Superfamily
Class Class 828

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand SB-213... 2 54
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 2 26
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Somatostatin receptor type 5 and Potassium voltage-gated chann... 2 21
5-hydroxytryptamine receptor 3A ligand 2-[(3S)-3-ethylmorpholi... 10 18
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Cannabinoid receptor 2 ligand 5-tert-butyl-2-[4-[3-chloro-5-(t... 1 1
Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-... 2 3
Melanin-concentrating hormone receptor 1 ligand N-[3-(2-aminoq... 4 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol... 3 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Prostaglandin E synthase inhibitor 1-[5-chloro-6-(4-fluorophen... 8 27
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 1
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 5 2
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
5-hydroxytryptamine receptor 6 ligand SureCN3910449 family 3 15
Somatostatin receptor type 5 ligand SureCN3572493 family 1 3


External ID

Functional Category

Molecule Name

CFAMM00386817 CHEMBL1800752 Bioactive [4-(5-tert-butyl-1,3-benzoxazol-2-yl)-1,4-diazepan-1-yl]-morpholin-4-ylmethanone
CFAMM00386816 CHEMBL1800753 Bioactive [4-(5-tert-butyl-1,3-benzoxazol-2-yl)-1,4-diazepan-1-yl]-(1,1-dioxo-1,4-thiazinan-4-yl)methanone
CFAMM00386819 CHEMBL1800750 Bioactive 1-[4-(5-tert-butyl-1,3-benzoxazol-2-yl)-1,4-diazepan-1-yl]-2-cyclopentylethanone
CFAMM00386818 CHEMBL1800751 Bioactive [4-(5-tert-butyl-1,3-benzoxazol-2-yl)-1,4-diazepan-1-yl]-(oxan-4-yl)methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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