CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8278
Family Name Mitogen-activated protein kinase 14 inhibitor 4-chloro-N-cyclopropyl-3-(2-oxospiro[1H-indole-3,1'-cyclopentane]-6-yl)benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00386846 Functional Category Bioactive
Superfamily Histamine H3 receptor and Vasopressin V2 receptor Binder Superfamily
Class Class 3113

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 13 42
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [2... 2 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-3-... 2 0
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
P2X purinoceptor 7 inhibitor 2-[3-fluoro-4-(trifluoromethyl)ph... 3 0
Tankyrase-2 inhibitor 3-chloro-N-(2-methoxyethyl)-4-(4-methyl-... 1 0
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 4
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-[2-(1-hydroxy-3... 3 0
P2X purinoceptor 7 inhibitor 2-[4-chloro-3-(trifluoromethyl)ph... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00386845 CHEMBL1800915 Bioactive 3-(5-chloro-2-oxospiro[1H-indole-3,1'-cyclopentane]-6-yl)-N-cyclopropylbenzamide
CFAMM00386846 CHEMBL1800913 Bioactive 4-chloro-N-cyclopropyl-3-(2-oxospiro[1H-indole-3,1'-cyclopentane]-6-yl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45247 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543