CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8305
Family Name Collagenase 3 and 72 kDa type IV collagenase inhibitor N-hydroxy-1-(pyridin-2-ylmethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpiperidine-4-carboxamide family
No. of Seeds 3 No. of Other Members 25
Family Centroid CFAMM00387015 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Interstitial collagenase Inhibitor Prinomastat Superfamily
Class Class 816

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 1 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 1 3
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387015 CHEMBL1801431 Bioactive N-hydroxy-1-(pyridin-2-ylmethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpiperidine-4-carboxamide
CFAMM00387014 CHEMBL80798 Bioactive N-hydroxy-4-(4-methoxyphenyl)sulfonyl-1-[(4-pyridin-2-ylphenyl)methyl]piperidine-4-carboxamide
CFAMM00387030 CHEMBL1801393 Bioactive N-hydroxy-1-(pyridin-3-ylmethyl)-4-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpiperidine-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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