CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8311
Family Name Type-1 angiotensin II receptor and Peroxisome proliferator-activated receptor gamma ligand 2-ethyl-7-methyl-5-(2-methylpropyl)-3-[(1S)-5-[2-(2H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl]imidazo[4,5-b]pyridine family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00290609 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-1B angiotensin II receptor Binder Superfamily
Class Class 3082

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
Type-1 angiotensin II receptor Ligand Losartan Family 3 90
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... 3 18
Aromatase and Thromboxane-A synthase Inhibitor 6-(1h-imidazol-... 3 8
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-2 angiotensin II receptor Ligand SC-50560 Family 3 84
Type-2 angiotensin II receptor Ligand SC-55634 Family 8 5
Xanthine dehydrogenase/oxidase Inhibitor 3,5-di(pyridin-4-yl)-... 6 3
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 12
Platelet-activating factor receptor ligand AGN-PC-0750SP family 4 0
Histamine H3 receptor ligand SureCN4025673 family 4 2
C-X-C chemokine receptor type 4 and Envelope glycoprotein gp16... 2 2
DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... 2 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Type-1B angiotensin II receptor ligand 2-[2-butyl-3-[[4-[2-(2H... 1 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14574... 1 2
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 6
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 4 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 1 0
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 13
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 5
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 1
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Adenosine receptor A1 ligand N-butyl-5-phenyl-3-[[2-(trifluoro... 7 2
Type-1 angiotensin II receptor ligand 5-[2-[4-[[4-butyl-3-[[4-... 4 2
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 3
D(3) dopamine receptor and Muscarinic acetylcholine receptor M... 8 2
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 16 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 0
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 10 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 4
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 35 14
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 9 2
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 2 0
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Type-1 angiotensin II receptor ligand SureCN7390271 family 2 1
Type-1B angiotensin II receptor ligand SureCN9309010 family 5 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 3
Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-prote... 2 0
Type-1 angiotensin II receptor ligand AGN-PC-04X8EF family 1 1
Gonadotropin-releasing hormone receptor ligand 4-[[4-[2-(4-ter... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27746 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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