CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8313
Family Name Nicotinamide phosphoribosyltransferase inhibitor 4-[[(7-chloro-3-methyl-4-oxoquinazolin-6-yl)amino]methyl]-N-(pyridin-3-ylmethyl)benzamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00387054 Functional Category Bioactive
Superfamily Nicotinamide phosphoribosyltransferase and Beta-secretase 1 Binder Superfamily
Class Class 1555

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
XL-888 family 16 85
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Amine oxidase [flavin-containing] B Inhibitor Lazebemide Family 2 13
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Nicotinamide phosphoribosyltransferase inhibitor 4-[(7-chloro-... 6 4
Coagulation factor X inhibitor AGN-PC-075AY8 family 28 21
Coagulation factor X inhibitor AGN-PC-078Y4E family 4 6
C-X-C chemokine receptor type 3 ligand SureCN13205646 family 4 0
Coagulation factor X and Kallikrein-1 inhibitor SureCN890858 f... 5 6
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Coagulation factor X inhibitor AGN-PC-078Y3A family 4 1
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 3 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (4-am... 2 1
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Coagulation factor X inhibitor 5-bromo-N-(5-chloropyridin-2-yl... 1 1
Coagulation factor X inhibitor AGN-PC-078Y0S family 7 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 0
Glutamate receptor 1 and Glutamate receptor 2 ligand cp-465022... 1 6
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Macrophage colony-stimulating factor 1 receptor ligand N-[3-[(... 5 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Potassium ... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387054 CHEMBL1801861 Bioactive 4-[[(7-chloro-3-methyl-4-oxoquinazolin-6-yl)amino]methyl]-N-(pyridin-3-ylmethyl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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