CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8315
Family Name Melatonin receptor type 1B and Melatonin receptor type 1A ligand N-[2-(2-phenyl-7,8-dihydrofuro[2,3-g]benzimidazol-1-yl)ethyl]acetamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00144636 Functional Category Bioactive
Superfamily Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-imidazol-1-yl-phenoxy)-propyl]-pyridine Superfamily
Class Class 976

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 7-et... 7 57
Oestrogen receptor and Estrogen receptor beta Ligand 4-(2-phen... 2 9
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 7 5
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
B2 bradykinin receptor ligand (E)-3-[6-(2-oxopyrrolidin-1-yl)p... 3 2
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Melanin-concentrating hormone receptor 1 ligand SureCN3334861 ... 1 3
Melatonin receptor type 1B ligand CHEMBL1802020 family 2 7
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 4 11
Glutamate receptor ionotropic, NMDA 2B ligand 2-[[4-(4-chlorop... 4 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 11 1
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
Aromatase inhibitor 2-(imidazol-1-ylmethyl)-6-methoxy-1-phenyl... 2 8
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 16 0
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Nociceptin receptor and Delta-type opioid receptor ligand 2-[3... 2 1
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN8919280 f... 23 18
Acyl-CoA:cholesterol acyltransferase inhibitor AGN-PC-00FHC0 f... 2 0
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2-(dimethyla... 2 1
Glucokinase inhibitor SureCN1657199 family 10 6


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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