CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8316
Family Name Melatonin receptor type 1A and Melatonin receptor type 1B ligand CHEMBL1802023 family
No. of Seeds 9 No. of Other Members 1
Family Centroid CFAMM00387072 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 9 and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 2449

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
PF-02545920 family 16 140
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Platelet-derived growth factor receptor alpha and Platelet-der... 2 14
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Sigma non-opioid intracellular receptor 1 ligand 1'-butyl-6-me... 23 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 5
Smoothened homolog inhibitor AGN-PC-088VBV family 1 2
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 6
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL15681... 1 5
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 2
Sigma non-opioid intracellular receptor 1 ligand 6-methoxy-1'-... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 0
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
Corticotropin-releasing factor receptor 1 ligand 2-(2-ethyl-4,... 4 9
Platelet-derived growth factor receptor beta and Receptor-type... 1 2
Platelet-derived growth factor receptor beta and Receptor-type... 6 5
Platelet-derived growth factor receptor beta and Macrophage co... 8 0
D(3) dopamine receptor and D(2) dopamine receptor ligand Piper... 3 14
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 5 14
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 6 4
Prostaglandin D2 receptor 2 ligand 2-[4-(difluoromethoxy)-2-et... 1 0
Serine/threonine-protein kinase Chk1 and Aurora kinase B inhib... 14 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
B2 bradykinin receptor ligand SureCN13145573 family 7 6
B2 bradykinin receptor and Cytochrome P450 3A4 ligand SureCN15... 4 0
Acetylcholinesterase and Cholinesterase inhibitor P10358 family 2 0
Serine/threonine-protein kinase pim-3 and Serine/threonine-pro... 4 6


External ID

Functional Category

Molecule Name

CFAMM00387068 CHEMBL1802027 Bioactive CHEMBL1802027
CFAMM00387074 CHEMBL1802028 Bioactive CHEMBL1802028
CFAMM00387066 CHEMBL1802029 Bioactive CHEMBL1802029
CFAMM00387073 CHEMBL1802022 Bioactive CHEMBL1802022
CFAMM00387065 CHEMBL1802030 Bioactive CHEMBL1802030
CFAMM00387072 CHEMBL1802023 Bioactive CHEMBL1802023
CFAMM00387071 CHEMBL1802024 Bioactive CHEMBL1802024
CFAMM00387070 CHEMBL1802025 Bioactive CHEMBL1802025
CFAMM00387069 CHEMBL1802026 Bioactive CHEMBL1802026

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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