CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8329
Family Name Elongation factor 1-alpha 1 and Elongation factor 1-alpha 2 inhibitor N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-4-[3-[(1R)-1-cyclohexylethyl]-2-(4-methoxyanilino)-8-oxopyrano[3,2-f]benzimidazol-6-yl]benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00387163 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Coagulation factor X Binder Superfamily
Class Class 1256

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor GSK461364 Family 40 84
B2 bradykinin receptor ligand SureCN7977402 family 5 6
B2 bradykinin receptor ligand (E)-3-[6-(2-oxopyrrolidin-1-yl)p... 3 2
B2 bradykinin receptor ligand SureCN8516699 family 3 2
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Coagulation factor X inhibitor AGN-PC-07C10A family 3 2
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
B2 bradykinin receptor ligand SureCN7976932 family 2 0
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Gastrin/cholecystokinin type B receptor ligand AGN-PC-077L8M f... 24 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387163 CHEMBL1802814 Bioactive N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-4-[3-[(1R)-1-cyclohexylethyl]-2-(4-methoxyanilino)-8-oxopyrano[3,2-f]benzimidazol-6-yl]benzamide
CFAMM00387162 CHEMBL1802815 Bioactive N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-4-[3-benzyl-2-(2-methylpropylamino)-8-oxopyrano[3,2-f]benzimidazol-6-yl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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