CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8344
Family Name Corticotropin-releasing factor receptor 1 ligand 5-(2,4-dichlorophenyl)-3,6-diethyl-N-pentan-3-ylpyrazin-2-amine family
No. of Seeds 5 No. of Other Members 17
Family Centroid CFAMM00387266 Functional Category Bioactive
Superfamily Reverse transcriptase and Amine oxidase [flavin-containing] A Binder Superfamily
Class Class 2257

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Transient receptor potential cation channel subfamily V member... 16 295
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
HCV NS4B protein Inhibitor Clemizole Family 2 43
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Sodium-dependent serotonin transporter Inhibitor 6-nitroquipaz... 18 21
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Bloom syndrome protein inhibitor SR 57227A family 2 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Thyrotropi... 1 2
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Cannabinoid receptor 1 ligand SureCN675796 family 5 1
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Corticotropin-releasing factor receptor 1 ligand 5-(2-chloro-4... 7 1
Dipeptidyl peptidase 4 inhibitor Aminomethylpyrimidine 1ck family 6 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 10
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... 4 0
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Mitogen-activated protein kinase 14 inhibitor pyrimido-pyrimid... 15 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... 5 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 0
Adenosine receptor A1 ligand 3-[(2-chlorophenyl)methyl]-N-cycl... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 2 0
Cannabinoid receptor 1 ligand AGN-PC-077JWI family 7 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
Nociceptin receptor and Potassium voltage-gated channel subfam... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387266 CHEMBL1806728 Bioactive 5-(2,4-dichlorophenyl)-3,6-diethyl-N-pentan-3-ylpyrazin-2-amine
CFAMM00387259 CHEMBL1807021 Bioactive 5-(2,4-dichlorophenyl)-N-(dicyclopropylmethyl)-3,6-diethylpyrazin-2-amine
CFAMM00387245 CHEMBL1807039 Bioactive 5-(2,4-dichlorophenyl)-3-ethyl-6-methyl-N-pentan-3-ylpyrazin-2-amine
CFAMM00387258 CHEMBL1807041 Bioactive 5-(2,4-dichlorophenyl)-3-methoxy-6-methyl-N-pentan-3-ylpyrazin-2-amine
CFAMM00387251 CHEMBL1807035 Bioactive 5-(2,4-dichlorophenyl)-6-ethyl-3-methoxy-N-pentan-3-ylpyrazin-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26841 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543