CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8349
Family Name Corticotropin-releasing factor receptor 1 ligand 5-(2-chloro-4-methoxyphenyl)-3-ethyl-6-methoxy-N-pentan-3-ylpyrazin-2-amine family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00387310 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Corticotropin-releasing factor receptor 1 Binder Superfamily
Class Class 2081

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 ligand 5-(2,4-dichlo... 5 17
Beta-secretase 1 and Amyloid beta A4 protein inhibitor SureCN3... 1 5


External ID

Functional Category

Molecule Name

CFAMM00387309 CHEMBL1807059 Bioactive 5-[2-chloro-4-(difluoromethoxy)phenyl]-3-ethyl-6-methoxy-N-pentan-3-ylpyrazin-2-amine
CFAMM00387308 CHEMBL1807056 Bioactive 5-(2-chloro-4-ethoxyphenyl)-3-methoxy-6-methyl-N-pentan-3-ylpyrazin-2-amine
CFAMM00387307 CHEMBL1807055 Bioactive 5-[2-chloro-4-(difluoromethoxy)phenyl]-3-methoxy-6-methyl-N-pentan-3-ylpyrazin-2-amine
CFAMM00387306 CHEMBL1807052 Bioactive 5-[2-chloro-4-(difluoromethoxy)phenyl]-6-ethyl-3-methoxy-N-pentan-3-ylpyrazin-2-amine
CFAMM00387305 CHEMBL1807042 Bioactive 5-(2,4-dichlorophenyl)-3,6-dimethoxy-N-pentan-3-ylpyrazin-2-amine
CFAMM00387311 CHEMBL1807048 Bioactive 5-(2,4-dichlorophenyl)-3-ethyl-6-methoxy-N-pentan-3-ylpyrazin-2-amine
CFAMM00387310 CHEMBL1807058 Bioactive 5-(2-chloro-4-methoxyphenyl)-3-ethyl-6-methoxy-N-pentan-3-ylpyrazin-2-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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