CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8358
Family Name Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 receptor EP4 subtype ligand SureCN7807282 family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00387372 Functional Category Bioactive
Superfamily Sodium- and Prostaglandin E2 receptor EP3 subtype Binder Superfamily
Class Class 4633

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Eprotirome family 11 50
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 160
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Prostaglandin D2 receptor 2 Ligand 2-(4-chloro-2-cyclohexylphe... 7 25
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387368 CHEMBL217988 Bioactive (E)-3-[2-[(E)-3-[2-[(2,6-dichlorophenyl)methoxy]-5-methylphenyl]prop-2-enyl]phenyl]prop-2-enoic acid
CFAMM00387367 CHEMBL360290 Bioactive SureCN7804184
CFAMM00387372 CHEMBL180742 Bioactive SureCN7807282
CFAMM00387371 CHEMBL183919 Bioactive SureCN7804198

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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