CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Histamine H1 receptor and Muscarinic acetylcholine receptor M1 ligand N,N-dimethyl-2-[3-[(1R)-1-(1,3-thiazol-2-yl)ethyl]-1H-inden-2-yl]ethanamine family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00316412 Functional Category Bioactive
Superfamily Histamine H1 receptor and Metabotropic glutamate receptor 5 Binder Superfamily
Class Class 2925

Cousin Family NamesSeedsMembers
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(thiazol-2-y... 4 5
Histamine H1 receptor and Potassium voltage-gated channel subf... 2 0
Histamine H1 receptor and Cytochrome P450 2D6 ligand N-methyl-... 1 0
Metabotropic glutamate receptor 5 ligand 2-Phenylethynyl-thiaz... 1 0


External ID

Functional Category

Molecule Name

CFAMM00316413 CHEMBL1092599 Bioactive N,N-dimethyl-2-[3-[(1R)-1-(4-methyl-1,3-thiazol-2-yl)ethyl]-1H-inden-2-yl]ethanamine
CFAMM00316412 CHEMBL1092598 Bioactive N,N-dimethyl-2-[3-[(1R)-1-(1,3-thiazol-2-yl)ethyl]-1H-inden-2-yl]ethanamine
CFAMM00316411 CHEMBL1090527 Bioactive 2-[6-fluoro-3-[(1R)-1-(1,3-thiazol-2-yl)ethyl]-1H-inden-2-yl]-N,N-dimethylethanamine
CFAMM00316410 CHEMBL1090528 Bioactive N,N-dimethyl-2-[6-methyl-3-[(1R)-1-(1,3-thiazol-2-yl)ethyl]-1H-inden-2-yl]ethanamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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