CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8361
Family Name Receptor-type tyrosine-protein kinase FLT3 and Vascular endothelial growth factor receptor 1 ligand N-[5-[3-[(3-chlorophenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00387409 Functional Category Bioactive
Superfamily Coagulation factor X and Coagulation factor IX Binder Superfamily
Class Class 3491

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Family 6 29
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Poly [ADP-ribose] polymerase 1 inhibitor 2-[2-[4-(1H-indazol-3... 1 0
Aurora kinase A inhibitor SureCN3894803 family 5 8
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 3 15
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 1 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 0
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 10 9
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(6-ph... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387409 CHEMBL1807467 Bioactive N-[5-[3-[(3-chlorophenyl)sulfonylamino]phenyl]-1H-pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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