CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8362
Family Name Receptor-type tyrosine-protein kinase FLT3 and Vascular endothelial growth factor receptor 1 ligand benzyl N-[[4-[3-[[4-(2-pyrrolidin-1-ylethoxy)benzoyl]amino]-1H-pyrazol-5-yl]phenyl]methyl]carbamate family
No. of Seeds 3 No. of Other Members 15
Family Centroid CFAMM00387416 Functional Category Bioactive
Superfamily Glycogen synthase kinase-3 beta Inhibitor N-(6-(furan-3-yl)-1h-indazol-3-yl)butyramide Superfamily
Class Class 1050

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Family 6 29
Fibroblast growth factor receptor 1 Ligand AZD4547 Family 1 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 6
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 1 0
Cyclin-dependent kinase 2 and Cyclin-A2 inhibitor N-(5-cyclopr... 3 7


External ID

Functional Category

Molecule Name

CFAMM00387416 CHEMBL2063324 Bioactive benzyl N-[[4-[3-[[4-(2-pyrrolidin-1-ylethoxy)benzoyl]amino]-1H-pyrazol-5-yl]phenyl]methyl]carbamate
CFAMM00387429 CHEMBL1807478 Bioactive N-[5-[3-(benzenesulfonamido)phenyl]-1H-pyrazol-3-yl]-4-(2-pyrrolidin-1-ylethoxy)benzamide
CFAMM00387422 CHEMBL2386797 Bioactive 4-(2-morpholin-4-ylethoxy)-N-[5-[4-[(phenylcarbamoylamino)methyl]phenyl]-1H-pyrazol-3-yl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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