CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8368
Family Name Sodium/glucose cotransporter 1 and Sodium/glucose cotransporter 2 inhibitor (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-cyclopropylphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00132174 Functional Category Bioactive
Superfamily Sodium/glucose cotransporter 2 and Sodium/glucose cotransporter 1 Binder Superfamily 2
Class Class 3237

Cousin Family NamesSeedsMembers
Sodium/glucose cotransporter 2 Inhibitor Empagliflozin Family 32 52
Glucokinase Inhibitor R7201 Family 22 105
TS-071 family 8 36
Sodium/glucose cotransporter 2 inhibitor (2S,3R,4R,5S,6R)-2-[4... 9 1
Estrogen receptor beta and Estrogen receptor ligand 3-chloro-4... 2 0
Sodium/glucose cotransporter 2 inhibitor (2S,3R,4R,5S,6R)-2-[3... 1 0
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387460 CHEMBL1807552 Bioactive (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-(1-hydroxycyclopropyl)phenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
CFAMM00387459 CHEMBL1807550 Bioactive 4-[[2-chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]benzonitrile
CFAMM00387457 CHEMBL1807548 Bioactive (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethynylphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27627 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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