CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8373
Family Name 3-oxoacyl-[acyl-carrier-protein] synthase 3 inhibitor 1-(2-methyl-5-nitroimidazol-1-yl)propan-2-yl (E)-3-(4-methoxyphenyl)prop-2-enoate family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00387488 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 Inhibitor GSK-644784 Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
Thromboxane-A synthase Inhibitor Dazoxiben Family 2 32
Aromatase Inhibitor 4'-cyano-3-(imidazolylmethyl)flavone Family 4 3
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Aromatase Inhibitor 4-(2-(1h-imidazol-1-yl)ethoxy)-2h-chromen-... 2 6
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(2-phenoxy-eth... 1 10
3-oxoacyl-[acyl-carrier-protein] synthase 3 inhibitor 1-(2-met... 11 6
Pol polyprotein inhibitor 162540-49-0 family 1 2
Thromboxane A2 receptor and Thromboxane-A synthase ligand 5-[(... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387488 CHEMBL1807656 Bioactive 1-(2-methyl-5-nitroimidazol-1-yl)propan-2-yl (E)-3-(4-methoxyphenyl)prop-2-enoate
CFAMM00387487 CHEMBL1807928 Bioactive 1-(2-methyl-5-nitroimidazol-1-yl)propan-2-yl (E)-3-(3-methoxyphenyl)prop-2-enoate
CFAMM00387486 CHEMBL1807658 Bioactive 1-(2-methyl-5-nitroimidazol-1-yl)propan-2-yl (E)-3-(4-phenylmethoxyphenyl)prop-2-enoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48713 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543