CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8378
Family Name Pol polyprotein inhibitor (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[4-(hydroxymethyl)phenyl]-6-(2-phenylethyl)-1,3-diazinan-2-one family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00387498 Functional Category Bioactive
Superfamily Sodium- and Glutamate receptor ionotropic, NMDA 2B Binder Superfamily
Class Class 3441

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor Dmp 323 family 11 44
Pol polyprotein inhibitor 3-[[(4R,5R,6R)-6-[2-(4-fluorophenyl)... 7 6
Pol polyprotein inhibitor 3-[(4R,5R,6R)-3-[3-[(E)-1-amino-2-hy... 2 4
Pol polyprotein inhibitor AC1LAMTL family 11 15
Pol polyprotein inhibitor 3-[(4R,5R,6R)-4-benzyl-3-(3-carbamoy... 3 1
Pol polyprotein inhibitor DMP-450 family 9 4
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 1 5
Pol polyprotein inhibitor AC1LAEIC family 3 3
Pol polyprotein inhibitor AC1LAMVF family 2 0
Neuropeptide Y receptor type 5 ligand 3-(4-benzylphenyl)-1-[(1... 2 4
Pol polyprotein inhibitor 4-benzyl-N-[(2S)-1-[[(2S,3R,4S,5S)-5... 3 0
Pol polyprotein inhibitor AC1LADP4 family 2 0
Pol polyprotein inhibitor AC1LAH82 family 2 1
Pol polyprotein inhibitor Cyclic Urea 73 family 2 0
C-C chemokine receptor type 3 ligand 1-(3-cyanophenyl)-3-[2-[2... 2 1


External ID

Functional Category

Molecule Name

CFAMM00387499 CHEMBL362069 Bioactive (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[3-(hydroxymethyl)phenyl]-6-(2-phenylethyl)-1,3-diazinan-2-one
CFAMM00387498 CHEMBL180816 Bioactive (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[4-(hydroxymethyl)phenyl]-6-(2-phenylethyl)-1,3-diazinan-2-one
CFAMM00387497 CHEMBL359753 Bioactive (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis(3-hydroxyphenyl)-6-(2-phenylethyl)-1,3-diazinan-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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