CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8382
Family Name Type-1 angiotensin II receptor and Type-2 angiotensin II receptor ligand AGN-PC-02JFWS family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00387524 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Type-2 angiotensin II receptor Binder Superfamily 11
Class Class 1331

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Tasosartan Family 10 29
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
TGF-beta receptor type-1 Ligand 4-(3-pyridin-2-yl-1h-pyrazol-4... 3 63
Histamine H4 receptor Ligand A-943931 Family 14 11
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Type-2 angiotensin II receptor Ligand SC-55634 Family 8 5
Corticotropin-releasing factor receptor 1 ligand 4-N-(2-bromo-... 9 48
Corticotropin-releasing factor receptor 1 ligand N-(2-bromo-4-... 5 0
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Adenosine receptor A1 ligand N-butyl-5-phenyl-3-[[2-(trifluoro... 7 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-met... 2 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 1
Corticotropin-releasing factor receptor 1 ligand 4-[7-(dipropy... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3
Type-1B angiotensin II receptor ligand SureCN9309010 family 5 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 3
Aurora kinase A inhibitor SureCN2205392 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00387529 CHEMBL32649 Bioactive AGN-PC-02JFWM
CFAMM00387533 CHEMBL32648 Bioactive AGN-PC-02JFX2
CFAMM00387527 CHEMBL33811 Bioactive SureCN9464440
CFAMM00387531 CHEMBL1808471 Bioactive [4-(4-methylphenyl)-2-(2-methylpropyl)-6-(2H-tetrazol-5-yl)quinolin-3-yl]methanamine;hydrochloride
CFAMM00387524 CHEMBL33459 Bioactive AGN-PC-02JFWS
CFAMM00387530 CHEMBL34044 Bioactive AGN-PC-02JFX8

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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