CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8394
Family Name C-X-C chemokine receptor type 3 ligand (6aR,9R)-9-(pyrrolidine-1-carbonyl)-N-thiophen-3-yl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00387594 Functional Category Bioactive
Superfamily Cytochrome P450 2D6 and C-C chemokine receptor type 3 Binder Superfamily
Class Class 2909

Cousin Family NamesSeedsMembers
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Transient receptor potential cation channel subfamily V member... 15 158
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Vascular endothelial growth factor receptor 2 and Receptor-typ... 7 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
C-X-C chemokine receptor type 3 ligand (6aR,9R)-N-phenyl-4-(2-... 5 0
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2


External ID

Functional Category

Molecule Name

CFAMM00387595 CHEMBL1809025 Bioactive (6aR,9R)-9-(pyrrolidine-1-carbonyl)-N-thiophen-2-yl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
CFAMM00387594 CHEMBL1809024 Bioactive (6aR,9R)-9-(pyrrolidine-1-carbonyl)-N-thiophen-3-yl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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