CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8399
Family Name Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 inhibitor 7-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-pyridin-4-yl-5H-thieno[3,2-c]pyridin-4-one family
No. of Seeds 1 No. of Other Members 14
Family Centroid CFAMM00387631 Functional Category Bioactive
Superfamily DNA-dependent protein kinase catalytic subunit and Aromatase Binder Superfamily
Class Class 2009

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Smoothened homolog Inhibitor LDE225 Family 3 76
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Histone deacetylase 1 Inhibitor ADS-102550 Family 3 5
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Renin Inhibitor CP-305202 Family 9 30
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 1 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Histamine H1 receptor and Potassium voltage-gated channel subf... 1 7
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Intercellular adhesion molecule 1 and E-selectin inhibitor Sur... 12 68
E-selectin and Intercellular adhesion molecule 1 inhibitor Sur... 5 5
cAMP-dependent protein kinase type II-alpha regulatory subunit... 2 4
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-[3-cy... 2 5
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Metabotropic glutamate receptor 1 ligand AGN-PC-046KML family 7 40
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 11 7
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 4 11
Acetylcholinesterase inhibitor 3-(1-benzylpyridin-1-ium-4-yl)-... 9 9
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 6 5
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Histone deacetylase 1 inhibitor 5-[5-[[2-(1-benzofuran-4-yl)et... 1 1
Metabotropic glutamate receptor 1 ligand SureCN8238253 family 9 0
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 4 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 3 15
Acetylcholinesterase inhibitor 1-(5,6-dimethoxy-1-benzothiophe... 2 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387631 CHEMBL1809114 Bioactive 7-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-pyridin-4-yl-5H-thieno[3,2-c]pyridin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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