CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8400
Family Name Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2-yl)-2-pyridin-4-yl-5H-thieno[3,2-c]pyridin-4-one family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00387644 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Mitogen-activated protein kinase 11 Binder Superfamily
Class Class 718

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Muscarinic acetylcholine receptor M4 Ligand VU10007 Family 2 17
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Deoxycytidine kinase inhibitor N-[(1S,3S)-3-(4-amino-5-fluoro-... 2 5
Vasopressin V2 receptor and Vasopressin V1a receptor ligand [2... 2 5
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-[4... 4 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745NK family 2 6
Sonic hedgehog protein inhibitor 3-chloro-N-[4-(methylamino)cy... 2 3
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 13 37
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9TG5 family 11 10
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 2
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[acetyl(thio... 6 3
C-C chemokine receptor type 5 ligand 6-chloro-2,4-dimethyl-N-[... 1 0
Histone deacetylase 1 inhibitor 5-[5-[[(2-chlorophenyl)methyla... 4 1
Metabotropic glutamate receptor 1 ligand SureCN8238697 family 2 0
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 4
Intercellular adhesion molecule 1 and E-selectin inhibitor Sur... 1 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 1
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1
Coagulation factor X inhibitor SureCN1253902 family 2 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387644 CHEMBL1809116 Bioactive 7-(6-chloropyridin-2-yl)-2-pyridin-4-yl-5H-thieno[3,2-c]pyridin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543