CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8404
Family Name Prothrombin and Transmembrane protease serine 11D inhibitor benzyl 4-[(4R)-4-(benzylsulfonylamino)-5-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]pyrrolidin-1-yl]-5-oxopentanoyl]piperazine-1-carboxylate family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00387654 Functional Category Bioactive
Superfamily Prothrombin and Coagulation factor X Binder Superfamily 3
Class Class 1271

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Prothrombin and Suppressor of tumorigenicity 14 protein inhibi... 5 8
Prothrombin inhibitor SureCN7341151 family 6 7
Prothrombin inhibitor (2S)-N-[4-(2-amino-2-iminoethyl)cyclohex... 2 0
Trypsin-1 and Urokinase-type plasminogen activator inhibitor (... 3 9
Prothrombin and Coagulation factor X inhibitor tert-butyl (4R)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387654 CHEMBL1809239 Bioactive benzyl 4-[(4R)-4-(benzylsulfonylamino)-5-[(2S)-2-[(4-carbamimidoylphenyl)methylcarbamoyl]pyrrolidin-1-yl]-5-oxopentanoyl]piperazine-1-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27649 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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