CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8406
Family Name Estrogen receptor and Estrogen receptor beta ligand (2R,3R,4S)-5-fluoro-3-(4-hydroxyphenyl)-4-methyl-2-[4-[(2S)-2-[(3R)-3-methylpyrrolidin-1-yl]propoxy]phenyl]-3,4-dihydro-2H-chromen-6-ol family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00387662 Functional Category Bioactive
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily 13
Class Class 142

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Acolbifene family 10 115
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Oestrogen receptor and Tyrosine-protein phosphatase non-recept... 92 21
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
Estrogen receptor and Estrogen receptor beta ligand CHEMBL1087... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOM... 2 5
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Transporter and 5-hydroxytryptamine receptor 2C ligand CHEMBL1... 5 5
Estrogen receptor and Estrogen receptor beta ligand SureCN3115... 9 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00E... 7 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Vesicular acetylcholine transporter inhibitor (2R,3R)-5-(3-flu... 2 0
Estrogen receptor and Estrogen receptor beta ligand SureCN8476... 2 1
Synaptic vesicular amine transporter inhibitor (2R)-3-[(2R,5S)... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387661 CHEMBL359671 Bioactive (2R,3R,4S)-5-fluoro-3-(4-hydroxyphenyl)-4-methyl-2-[4-[(2S)-2-[(3S)-3-methylpyrrolidin-1-yl]propoxy]phenyl]-3,4-dihydro-2H-chromen-6-ol
CFAMM00387660 CHEMBL359633 Bioactive SureCN6688172
CFAMM00387662 CHEMBL180995 Bioactive (2R,3R,4S)-5-fluoro-3-(4-hydroxyphenyl)-4-methyl-2-[4-[(2S)-2-[(3R)-3-methylpyrrolidin-1-yl]propoxy]phenyl]-3,4-dihydro-2H-chromen-6-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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