CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8409
Family Name Beta-3 adrenergic receptor and Beta-1 adrenergic receptor ligand SureCN7532101 family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00231993 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily 4
Class Class 3302

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Formoterol Family 16 63
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
Beta-2 adrenergic receptor Ligand Olodaterol Family 16 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Beta-3 adrenergic receptor Ligand Cgp 12177 Family 3 8
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Histamine H3 receptor Ligand UCL1972 Family 3 23
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Beta-1 adrenergic receptor ligand 1-[2-[[(2S)-3-(2-cyanophenox... 10 4
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 2
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Beta-1 adrenergic receptor ligand 4-[2-[[(2S)-3-(2-cyano-5-flu... 3 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 0
Transient receptor potential cation channel subfamily V member... 3 15
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Sodium-dependent serotonin transporter inhibitor SureCN3890472... 2 0
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 16 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
Androgen receptor ligand AGN-PC-00BRQF family 2 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 4 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-[(4... 10 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-[(2... 2 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospi... 4 0
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 8
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-[4-[3... 2 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 1 0
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 8 0
Beta-1 adrenergic receptor and Beta-3 adrenergic receptor liga... 2 0
DNA polymerase III PolC-type inhibitor 6-(3-ethyl-4-methylanil... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387686 CHEMBL369346 Bioactive 1-[4-[(2S)-3-hydroxy-2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]propyl]phenyl]-3-(3-nitrophenyl)urea
CFAMM00387684 CHEMBL183307 Bioactive 1-[4-[(2S)-3-hydroxy-2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]propyl]phenyl]-3-(4-methoxyphenyl)urea
CFAMM00387687 CHEMBL183611 Bioactive SureCN6539731

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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