CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM841
Family Name Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor SureCN4387298 family
No. of Seeds 9 No. of Other Members 3
Family Centroid CFAMM00316453 Functional Category Bioactive with Natural Product
Superfamily Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Binder Superfamily 2
Class Class 1256

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand BIIB014 Family 26 92
MK-3328 family 2 32
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Coagulation factor X and Prothrombin Inhibitor BMS-344577 Family 13 12
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 14
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Serine/threonine-protein kinase pim-1 inhibitor (2Z)-6-methoxy... 1 5
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00316460 CHEMBL1091705 Bioactive SureCN4392448
CFAMM00316453 CHEMBL1091697 Bioactive SureCN4387298
CFAMM00316459 CHEMBL1091706 Bioactive SureCN4381151
CFAMM00316458 CHEMBL1091703 Bioactive SureCN4384423
CFAMM00316457 CHEMBL1091702 Bioactive SureCN4380737

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27163 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543