CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8417
Family Name Fatty-acid amide hydrolase 1 inhibitor (1R)-2-[[6-(3-chloro-4-ethoxyphenyl)pyrimidin-4-yl]amino]-1-phenylethanol family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00387731 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Binder Superfamily
Class Class 2955

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Melanin-concentrating hormone receptor 1 Ligand ADS-102891 Family 6 51
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 6 47
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
Dual specificity protein kinase CLK1 and Dual specificity prot... 2 14
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase inhibitor SureCN7818675 family 7 14
Methionine--tRNA ligase inhibitor 2-({3-[(3,5-Dichlorobenzyl)a... 5 7
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Dihydrofolate reductase inhibitor 7-(5-chloro-2-ethoxyphenyl)-... 2 1
Vascular endothelial growth factor receptor 2 and Serine/threo... 1 2
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 3 5
Transient receptor potential cation channel subfamily V member... 2 4
Transient receptor potential cation channel subfamily V member... 2 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 4 24
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 10 4
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 0
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 2
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387731 CHEMBL1812715 Bioactive (1R)-2-[[6-(3-chloro-4-ethoxyphenyl)pyrimidin-4-yl]amino]-1-phenylethanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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