CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8418
Family Name Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-2-yl)-5-(1-ethylindol-5-yl)-1,3-benzoxazole family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00387737 Functional Category Bioactive
Superfamily Integrin alpha-4 and Cathepsin S Binder Superfamily
Class Class 678

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Smoothened homolog Inhibitor LDE225 Family 3 76
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Inosine-5'-monophosphate dehydrogenase 2 inhibitor [2-[N-methy... 1 18
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Transient receptor potential cation channel subfamily V member... 7 5
Aurora kinase A inhibitor SureCN761045 family 2 0
5-hydroxytryptamine receptor 3A ligand 2-[(3S)-3-ethylmorpholi... 10 18
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-... 4 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol... 3 4
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Scavenger receptor class B member 1 ligand 2-[9-[3-(4,6-dimeth... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
5-hydroxytryptamine receptor 6 ligand SureCN3910449 family 3 15
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077D0D family 3 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00387737 CHEMBL1812716 Bioactive 2-(1,3-dihydroisoindol-2-yl)-5-(1-ethylindol-5-yl)-1,3-benzoxazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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