CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8427
Family Name Beta-2 adrenergic receptor and Beta-3 adrenergic receptor ligand [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(2-methylprop-2-enylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate family
No. of Seeds 9 No. of Other Members 22
Family Centroid CFAMM00387836 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily
Class Class 3059

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 16 2
Beta-3 adrenergic receptor ligand 4,5-dichloro-N-[3-[(1R)-1-hy... 4 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 0
Beta-3 adrenergic receptor ligand 2-amino-N-[3-[(1R)-1-hydroxy... 7 0
Beta-3 adrenergic receptor ligand 3-[2-[[(2R)-2-(3-chloropheny... 1 1
Beta-secretase 1 and Beta-secretase 2 inhibitor CHEMBL554146 f... 1 2


External ID

Functional Category

Molecule Name

CFAMM00387847 CHEMBL182018 Bioactive [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-[[(E)-3-phenylprop-2-enyl]amino]phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387840 CHEMBL425161 Bioactive [3-[(2R)-2-[[(2R)-2-[3-[[(E)-but-2-enyl]amino]phenyl]-2-hydroxyethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387833 CHEMBL181440 Bioactive [3-[(2R)-2-[[(2R)-2-[3-(benzenesulfonamido)phenyl]-2-hydroxyethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387839 CHEMBL360133 Bioactive [3-[(2R)-2-[[(2R)-2-[3-(but-2-ynylamino)phenyl]-2-hydroxyethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387832 CHEMBL181300 Bioactive [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(prop-2-ynylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387845 CHEMBL182689 Bioactive [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(prop-2-enylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387837 CHEMBL183552 Bioactive [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(naphthalen-2-ylmethylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387843 CHEMBL181603 Bioactive [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-[[(E)-pent-2-enyl]amino]phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate
CFAMM00387836 CHEMBL181964 Bioactive [3-[(2R)-2-[[(2R)-2-hydroxy-2-[3-(2-methylprop-2-enylamino)phenyl]ethyl]amino]propyl]-1H-indol-7-yl] methanesulfonate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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