CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8453
Family Name Glucocorticoid receptor ligand [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-phenylmethanol family
No. of Seeds 27 No. of Other Members 33
Family Centroid CFAMM00388102 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Carbonic anhydrase 9 Binder Superfamily
Class Class 4640

Cousin Family NamesSeedsMembers
Glucocorticoid receptor Ligand 1-(3-chloro-4-fluorophenyl)-2,2... 1 13
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 10
DNA-(apurinic or apyrimidinic site) lyase and Ras-related prot... 1 6
Glucocorticoid receptor ligand [(4aR,5S)-1-(4-fluorophenyl)-4a... 7 1
Glucocorticoid receptor ligand SureCN12956559 family 11 0
Glucocorticoid receptor ligand SureCN13477113 family 19 3
Glucocorticoid receptor ligand CHEMBL2022651 family 3 1
Glucocorticoid receptor ligand 2-[2-[(4aS,5R)-1-(4-fluoropheny... 16 3
Casein kinase I isoform delta and Casein kinase I isoform epsi... 1 0
Progesterone receptor ligand AGN-PC-074LX4 family 1 4
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388066 CHEMBL310420 Bioactive SureCN10116149
CFAMM00388092 CHEMBL186805 Bioactive 1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-3-phenylpropan-1-ol
CFAMM00388105 CHEMBL311034 Bioactive SureCN12956236
CFAMM00388059 CHEMBL81111 Bioactive SureCN12956166
CFAMM00388111 CHEMBL79807 Bioactive SureCN10116155
CFAMM00388091 CHEMBL310365 Bioactive SureCN13581497
CFAMM00388071 CHEMBL312041 Bioactive 2-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]propan-2-ol
CFAMM00388097 CHEMBL79335 Bioactive (1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]pent-4-en-1-ol
CFAMM00388110 CHEMBL309243 Bioactive (1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]but-3-en-1-ol
CFAMM00388083 CHEMBL419479 Bioactive SureCN13581479
CFAMM00388089 CHEMBL82546 Bioactive SureCN12956385
CFAMM00388102 CHEMBL181601 Bioactive [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-phenylmethanol
CFAMM00388115 CHEMBL186683 Bioactive 1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]pentan-1-ol
CFAMM00388069 CHEMBL83110 Bioactive SureCN13581509
CFAMM00388095 CHEMBL81591 Bioactive SureCN11995501
CFAMM00388108 CHEMBL312399 Bioactive SureCN13581526
CFAMM00388062 CHEMBL364015 Bioactive SureCN12956302
CFAMM00388075 CHEMBL420767 Bioactive SureCN13586678
CFAMM00388081 CHEMBL362392 Bioactive 1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-2-phenylethanol
CFAMM00388094 CHEMBL233389 Bioactive cyclopenta[f]indazole, 9
CFAMM00388061 CHEMBL183475 Bioactive 1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]nonan-1-ol
CFAMM00388113 CHEMBL583629 Bioactive (1S)-1-[(4aR)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]but-3-en-1-ol
CFAMM00388067 CHEMBL362556 Bioactive [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(4-chlorophenyl)methanol
CFAMM00388093 CHEMBL184109 Bioactive [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(4-fluorophenyl)methanol
CFAMM00388106 CHEMBL311662 Bioactive (1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-1-(4-fluorophenyl)ethanol
CFAMM00388073 CHEMBL186954 Bioactive [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-(4-methylphenyl)methanol
CFAMM00388099 CHEMBL186948 Bioactive [(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-5,6,7,8-tetrahydro-4H-benzo[f]indazol-5-yl]-naphthalen-2-ylmethanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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