CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8456
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]pyrrolidine-2-carbonyl]amino]benzoic acid family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00388128 Functional Category Bioactive with Natural Product
Superfamily Integrin beta-1 and Aldose reductase Binder Superfamily
Class Class 257

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Cholecystokinin receptor type A Ligand Gi 181771 Family 3 18
Intedanib family 7 54
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Tyrosine-protein kinase SYK Inhibitor N-benzyl-4-(2,5-dihydrox... 1 4
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 3 3
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 5 2
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 14
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Chymase and Chymotrypsin-C inhibitor 3-[[2,2-difluoro-4-[[(2S)... 6 10
Gastrin/cholecystokinin type B receptor ligand 3-[3-[[2-[5-cyc... 7 2
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 24b family 1 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 22
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 12 13
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-[2-[... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2-chlo... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Type-2 angiotensin II receptor ligand (2S)-4-(dipentylcarbamoy... 1 0
Aldose reductase inhibitor ethyl 3-methyl-2,2',5'-trioxospiro[... 1 2
Putative NP ZINC32123992 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388124 CHEMBL435774 Bioactive 4-[[(2S)-3-methyl-1-oxo-1-[2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)carbamoyl]pyrrolidin-1-yl]butan-2-yl]carbamoylamino]benzoic acid
CFAMM00388128 CHEMBL181652 Bioactive 4-[[1-[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]acetyl]pyrrolidine-2-carbonyl]amino]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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