CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM8471
Family Name Substance-P receptor ligand 3-[bis(4-fluorophenyl)methyl]-1-[(2,5-dimethoxyphenyl)methyl]piperidin-4-one;hydrochloride family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00388218 Functional Category Bioactive with Natural Product
Superfamily Substance-P receptor Binder Superfamily 5
Class Class 2973

Cousin Family NamesSeedsMembers
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Substance-P receptor Ligand Ezlopitant Family 10 207
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Histamine H3 receptor Ligand A-349821 Family 49 228
Caspase-3 Inhibitor 2-(4-methoxy-benzyl)isoquinoline-1,3,4-tri... 2 2
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Endothelin-1 receptor and Endothelin B receptor ligand (2R,3R,... 5 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
Substance-P receptor ligand 3-[bis(4-fluorophenyl)methyl]-1-[(... 2 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Nuclear receptor ROR-gamma ligand 3-(1,3-benzodioxol-5-yl)-1-(... 3 36
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00388217 CHEMBL1817887 Bioactive 3-[bis(4-fluorophenyl)methyl]-1-[(2,6-dimethoxyphenyl)methyl]piperidin-4-one;hydrochloride
CFAMM00388221 CHEMBL1817891 Bioactive 3-benzhydryl-1-[[2-methoxy-5-(trifluoromethoxy)phenyl]methyl]piperidin-4-one;hydrochloride
CFAMM00388220 CHEMBL1817890 Bioactive 3-[bis(4-fluorophenyl)methyl]-1-[[2-methoxy-5-(trifluoromethoxy)phenyl]methyl]piperidin-4-one;hydrochloride
CFAMM00388219 CHEMBL1817885 Bioactive 3-[bis(4-fluorophenyl)methyl]-1-[(2,4-dimethoxyphenyl)methyl]piperidin-4-one;hydrochloride
CFAMM00388218 CHEMBL1817886 Bioactive 3-[bis(4-fluorophenyl)methyl]-1-[(2,5-dimethoxyphenyl)methyl]piperidin-4-one;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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